/01/Trillion imagination The term “synthetic biology” first appeared in the 1970s, until it was redefined by Stanford professor Eric Kool in 2000 by introducing engineering concepts based on genomics and systems biology, marking the emergence of this discipline. Simply put, synthetic biology is the use of engineered organisms such as bacteria to produce various…
Sulfur-containing natural products (sulfur-containing NPs) cover almost every type of NP discovered so far. The source of sulfur in peptide NPs is usually composed of cysteine and methionine. Methionine can be directly incorporated into peptide NPs without any modification, such as precarriebowamide (1). The cysteine residues in peptide NPs are typically embedded in intramolecular disulfides,…
1) Introduction to L-malic acid Malic acid, also known as 2-hydroxysuccinic acid, has an asymmetric carbon hydroxysuccinic acid in its molecule, which has two stereoisomers and exists in three forms: L-malic acid, DL malic acid, and D-malic acid. It can be widely used in fields such as food and beverage, medicine, and chemical industry. Currently,…
The drawbacks of traditional microbial fermentation processes include the risk of contamination by harmful microorganisms, the inhibitory effect of high concentration carbon sources in the culture medium, microbial thermal sensitivity, and instability. And low yield and productivity, low substrate utilization efficiency, production of by-products and secondary metabolites, or high downstream processing costs. In order to…
The definition of synthetic biology is to use engineering ideas to modularize or create biological cells, enabling them to have the ability to synthesize compounds. Generalized synthetic biology actually refers to the extension of a series of downstream technologies based on DNA editing technology, including microbial metabolic engineering, enzyme engineering, gene editing services, cell therapy…
In recent years, with the changes in human environment and diseases, the incidence of fungal infections has been increasing year by year. Candida albicans is one of the important pathogens causing fungal infections. In addition, it is also an important food-borne pathogen.